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March 2013 - Volume 7, Issue 3

 

In this issue...

-  Vitamin D protects telomeres: a randomized, controlled trial

-  Vitamin C helps antidepressant drug work better

-  Serine improves ADHD symptoms

-  Are micronutrients underrated in assisted reproduction?

-  Study sheds light on CoQ10's role in healthy sperm

                                                                                                                                                 

 

 

 

CLINICAL UPDATE - Vitamin D protects telomeres: a randomized, controlled trial

Telomerase activity was measured before and after 37 people were given either placebo or about 2000IU of oral vitamin D supplements per day for 16 weeks.  Serum vitamin D levels for those taking the supplement increased almost 200%.  The telomerase activity increased over 19% as well, while the telomerase activity of those on placebo did not change.

(International Journal of Obesity, June 2012)

LINK to ABSTRACT  Increased telomerase activity and vitamin D supplementation in overweight African Americans.
LINK to FLYER on NUTRIENT INTERACTIONS IN TELOMERES


 

 

 

CLINICAL UPDATE - Vitamin C helps antidepressant drug work better

In this randomized, double-blind, placebo controlled trial, a group of patients with major depressive disorder (n=12) were given fluoxetine plus 1000mg of vitamin C daily and compared to a group (n=12) that were given fluoxetine plus placebo.  After six months, those receiving vitamin C in conjunction with fluoxetine showed a significant decrease in symptoms when evaluated using three different standardized depression rating systems compared to the placebo group.

(Nutrition Journal, March 2013)

LINK to ABSTRACT Efficacy of vitamin C as an adjunct to fluoxetine therapy in pediatric major depressive disorder: a randomized, double-blind, placebo-controlled pilot study.
LINK to FREE FULL TEXT
LINK to FLYER on NUTRIENT INTERACTIONS IN DEPRESSION


 

 

 

CLINICAL UPDATE - Serine improves ADHD symptoms

In this randomized, double-blind trial, 36 children diagnosed with ADHD received either 200mg of phosphatidylserine or placebo daily for two months.  Those receiving phosphatidylserine showed improved memory, attention and control of impulses compared to placebo.  Serine’s key role in psychiatric and neurological health has been gaining attention from studies such as this.  The authors concluded that phosphatidylserine “may be a safe and natural nutritional strategy for improving mental performance.”

(Journal of Human Nutrition and Dietetics, March 2013)

LINK to ABSTRACT The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial.
LINK to FLYER on NUTRIENT INTERACTIONS IN ADHD

 

 

 

 

CLINICAL UPDATE - Are micronutrients underrated in assisted reproduction?

Several recent studies are suggesting that micronutrient status prior to and during pregnancy should get more attention.  One study showed that low blood values of B vitamins and high homocysteine in mid pregnancy reduced fetal growth rates.  Another study showed that low homocysteine, determined by B vitamin status, was linked to a better chance of pregnancy in women undergoing assisted reproduction.  Yet another study showed that subfertile women undergoing ovulation induction who were taking a multi-micronutrient vitamin were more likely to get pregnant than women who took only a folic acid supplement.  Finally, a recently published review demonstrates how increasing a woman’s ability to fight oxidative stress increases her chances of successful pregnancy via assisted reproduction.

(Maternal and Child Nutrition, April 2013)
(Journal of Assisted Reproduction and Genetics, April 2012)
(Reproductive Biomedicine Online, January 2012)
(Reproductive Biology and Endocrinology, June 2012)

LINK to ABSTRACT Folate, Vitamin B12, Vitamin B6 and homocysteine: impact on pregnancy outcome.

LINK to ABSTRACT The association between homocysteine in the follicular fluid with embryo quality and pregnancy rate in assisted reproductive techniques.

LINK to ABSTRACT  Prospective randomized trial of multiple micronutrients in subfertile women undergoing ovulation induction: a pilot study.

LINK to ABSTRACT The effects of oxidative stress on female reproduction: a review.

LINK to FREE FULL TEXT

LINK to FLYER on NUTRIENT INTERACTIONS IN FEMALE FERTILITY

 

 

 

 

 

CLINICAL UPDATE - Study sheds light on CoQ10's role in healthy sperm

Sixty infertile men were given 200mg of CoQ10 or placebo for 3 months.  CoQ10 lowered oxidative stress in semen (measured by isoprostanes and superoxide dismutase activity) and improved sperm function significantly.

(Andrologia, January 2013)

LINK to ABSTRACT Effect of Coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: a double-blind randomised clinical trial.