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July 2011 - Volume 5, Issue 7

 

In this issue...

- CoQ10 improves brain bioenergetics

- Vitamin E elongates telomeres

- Carnitine reduces severity of autism

- Inositol helps control gestational diabetes

- Vitamin D and zinc lower prostate cancer mortality risk

- Low vitamin C linked to cataract

 

In SpectraCell News...

- Telomere Testing Goes Mainstream.  Read more...

- To see SpectraCell Labs Featured on NBC Today Show CLICK HERE

 

 

 

                                                                                                                                                 

 

 

 

CLINICAL UPDATE - CoQ10 improves brain bioenergetics

Recent research shows CoQ10 to have clinical benefit in both migraine prevention and protection against injury that occurs from lack of blood flow to the brain (as in stroke).  Specifically, a randomized controlled trial on 120 children with migraines showed that 100mg of CoQ10 reduced the frequency of migraine headaches, but only in the first four weeks of supplementation. In another  study, CoQ10 therapy given after brain ischemia reduced damage from oxidative stress that occurs after such injuries, and it also increased the concentrations of vitamin E in both the brain mitochondria and blood.

(Cephalalgia, June 2011)

(Current Alzheimers Research, May 2011)

LINK to ABSTRACT A randomized, double-blinded, placebo-controlled, crossover, add-on study of CoEnzyme Q10 in the prevention of pediatric and adolescent migraine.

LINK to ABSTRACT Effects of Coenzyme Q and Creatine Supplementation on Brain Energy Metabolism in Rats Exposed to Chronic Cerebral Hypoperfusion.

 

 

 

 

CLINICAL UPDATE - vitamin e elongates telomeres

When human connective tissue cells were treated in vitro with vitamin E, researchers observed a reduction in the amount of damaged DNA with a concurrent increase in telomerase activity and elongated telomeres. This confirms other evidence that nutritional status affects telomere length.

(Journal of Biomedicine and Biotechnology, March 2011)
(Journal of Nutritional Biochemistry, March 2011)

(Clinical Science, May 2011)

LINK to ABSTRACT Tocotrienol-rich fraction prevents cell cycle arrest and elongates telomere length in senescent human diploid fibroblasts.

LINK to FREE FULL TEXT 

LINK to ABSTRACT Diet, nutrition and telomere length.

LINK to ABSTRACT Healthy aging and disease: role for telomere biology?

LINK to FREE FULL TEXT 

 

 

 

 

CLINICAL UPDATE - carnitine reduces severity of autism

In a prospective double-blind, randomized clinical trial on thirty autistic patients, 50mg (per kilogram body weight) per day of L-carnitine therapy given for three months improved symptoms of autism such as cognitive function and muscle control.

(Medical Science Monitor, June 2011)

LINK to ABSTRACT A prospective double-blind, randomized clinical trial of levocarnitine to treat autism spectrum disorders.

 

 

 

 

CLINICAL UPDATE - inositol helps control gestational diabetes

Inositol was given (4g daily) for eight weeks to a group of pregnant women with diagnosed gestational diabetes and compared to a control group that was not supplemented with inositol, but that also had gestational diabetes.  Those treated with inositol had significantly lower fasting blood glucose and insulin while levels of the fat-burning hormone adiponectin increased compared to the non-supplemented group.

(Diabetic Medicine, August 2011)

LINK to ABSTRACT The effect of myoinositol supplementation on insulin resistance in patients with gestational diabetes.

 

 

 

 

CLINICAL UPDATE - Vitamin D and Zinc Lower prostate cancer mortality risk

In two separate American studies, higher vitamin D levels and a higher intake of dietary zinc significantly reduced the risk of prostate cancer specific mortality. Specifically, there was about a 20% increase in mortality risk for the men with the lowest levels of vitamin D and a 50% increase in mortality risk for men with the lowest intakes of dietary zinc, compared to those with the highest levels.

(PLoS One, April 2011)
(American Journal of Clinical Nutrition, March 2011)

LINK to ABSTRACT Prediagnostic Plasma Vitamin D Metabolites and Mortality among Patients with Prostate Cancer.

LINK to FREE FULL TEXT 

LINK to ABSTRACT  Dietary zinc and prostate cancer survival in a Swedish cohort.

 

 

 

CLINICAL UPDATE - Low vitamin C linked to cataract

Levels of vitamin C were measured in the blood of over 5600 people over the age of sixty.  Among antioxidants measured (vitamin C, vitamin A, lutein and zeaxanthin), all had an inverse association with cataract but vitamin C showed the strongest link and this association was consistently observed by type of cataract as well.

(Ophthalmology, June 2011)

LINK to ABSTRACT Inverse Association of Vitamin C with Cataract in Older People in India.