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December 2009 - Volume 3, Issue 12


In this issue...

- Choline deficiency prevalent among Americans

- Magnesium reduces inflammation

- Maternal folate status linked to hyperactive children

- Amount of vitamin D needed to correct deficiency depends on weight

- Magnesium reduces fat absorption after meals





CLINICAL UPDATE - Choline deficiency prevalent among americans

A recent review of choline, a deficiency in which is associated with atherosclerosis, liver disease and neurological problems, concludes that most Americans do not reach the requirements for choline set by the Institute of Medicine and widespread deficiencies exist as a result.

            (Nutrition Reviews, November 2009)
LINK to ABSTRACT  Choline: an essential nutrient for public health.





CLINICAL UPDATE - Magnesium reduces inflammation

After blood samples in over 3700 postmenopausal women were evaluated, researchers found that magnesium intake was inversely associated with four major inflammatory markers including hs-CRP and IL-6, and that endothelial dysfunction was positively affected as a result.

(Diabetes Care, November 2009)     

LINK to ABSTRACT Relations of dietary magnesium intake to biomarkers of inflammation and endothelial dysfunction in an ethically diverse cohort of postmenopausal women





CLINICAL UPDATE - maternal folate status linked to hyperactive children

A recent study of 100 mothers whose children were evaluated for an average of 8.75 years revealed that lower maternal folate status was associated with higher childhood hyperactivity and behavioral problems in their offspring.

(Journal of Childhood Psychology and Psychiatry, October 2009)     

LINK to ABSTRACT Lower maternal folate status in early pregnancy is associated with childhood hyperactivity and peer problems in offspring.





CLINICAL UPDATE - Amount of vitamin D needed to correct deficiency depends on weight

In an outpatient study on 95 people, the amount of vitamin D needed to replete a severe deficiency was largely dependent on body mass index – the more overweight the person, the more vitamin D that was necessary to correct the deficiency.

(The American Journal of Medicine, November 2009)     

LINK to ABSTRACT Adequacy of vitamin D replacement in severe deficiency is dependent on    body mass index.





CLINICAL UPDATE - magnesium reduces fat absorption after meals

Lipids were measured on 16 healthy males who consumed butter that was supplemented with magnesium and butter with no supplement.  Blood samples were taken at 2 hour intervals after ingestion and researchers found that triglycerides, remnant lipoprotein and fatty acids were all lower in the magnesium-supplemented fat meal compared to the fat-only meal.

(British Journal of Nutrition, November 2009)     

LINK to ABSTRACT  Effects of magnesium on postprandial serum lipid responses in healthy      human subjects.