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March 2009 - Volume 3, Issue 03

 

In this issue...

- Antioxidant therapy alleviates severe psoriasis

- Zn, Ca and Mg reduce type 2 diabetes risk

- Does Lp(a) promote tumor growth?

- Vitamin C helps prevent gout

- Glutamine maintains intestinal barrier

                                                                                                                                                 

 

 

CLINICAL UPDATE - Antioxidant therapy alleviates severe psoriasis

58 patients with severe psoriasis were hospitalized and treated with either a placebo or a mixture of CoQ10, vitamin E and selenium. Supplementation significantly improved clinical symptoms while simultaneously lowering markers of oxidative stress.

(Nutrition, March 2009)

Link to ABSTRACT: Clinical and biochemical effects of coenzyme Q10, vitamin E and selenium supplementation to psoriasis patients.

 

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CLINICAL UPDATE - Zn, Ca and Mg reduce type 2 diabetes risk

One study followed more than 82,000 nurses aged 33-60 years for 24 years and found higher zinc intake was associated with a slightly lower risk of type 2 diabetes.  Another study followed more than 64,000 Chinese women and found that higher calcium and magnesium intake protected against the development of type 2 diabetes.

(Diabetes Care, January 2009)

(American Journal of Clinical Nutrition, February 2009)

Link to ABSTRACT: A Prospective Study of Zinc Intake and Risk of Type 2 Diabetes in Women

Link to ABSTRACT: Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health Study.

 

 

CLINICAL UPDATE - Does Lp(a) promote tumor growth?

Researchers measured Lp(a) levels on 418 men with lung cancer and found they had significantly higher levels of Lp(a) than healthy controls, supporting the claim that Lp(a) plays an important role in the development of tumors.

(Clinical Chemistry and Laboratory Medicine, February 2009)

Link to ABSTRACT: Lipoprotein(a) level and its association with tumor state in male patients with primary lung cancer.

 

 

 

CLINICAL UPDATE - Vitamin c helps prevent gout

Nearly 47,000 men were followed for 20 years and showed that a higher vitamin C intake, which has been shown in previous trials to reduce uric acid levels, significantly lowered the risk of gout.

(Archives of Internal Medicine, March 2009)

Link to ABSTRACT: Vitamin C Intake and the Risk of Gout in Men: A Prospective Study.

 

 

 

CLINICAL UPDATE - Can vitamin d lower rates of infection?

Since recent studies have suggested a role of vitamin D in immunity, a group of researchers looked at the association of vitamin D levels and upper respiratory tract infections (URTI) in nearly 19,000 people and found vitamin D levels to be independently associated with URTI, especially in people with asthma and chronic respiratory diseases.

(Archives of Internal Medicine, February 2009)

Link to ABSTRACT: Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey.

 

 

 

CLINICAL UPDATE - Glutamine maintains intestinal barrier

Glutamine deficiency has long been associated with increased gut permeability and recent work reveals the specific mechanism of how glutamine protects the intestinal barrier.

(Journal of Nutrition, February 2009)

Link to ABSTRACT: Glutamine Deprivation Alters Intestinal Tight Junctions via a PI3-K/Akt Mediated Pathway in Caco-2 Cells.