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March 2008 - Volume 2, Issue 03

 

In this issue...

- Science stacks up for B vitamins and pregnancy

- LDL particles are better treatment target than LDL cholesterol

- Body mass index linked with cancer

- Common antioxidant helps prevent breast cancer

- Vitamin D and omega 3 protect children from diabetes

- Magnesium reduces risk of gallstones in men

                                                                                                                                                

 

 

 

CLINICAL UPDATE - Science stacks up for b vitamins and pregnancy

Low maternal vitamin B12 levels may increase risk of congenital heart problems; Folic acid may help prevent premature birth and placental abruption

(Molecular Genetics and Metabolism, January 2008)

(American Journal of Epidemiology, January 2008)

(Society of Maternal-Fetal Medicine Annual Meeting Proceedings, January 2008)

Link to ABSTRACT: Genetic and lifestyle factors related to periconception vitamin B12 status and congenital heart defects: A Dutch case-control study.

Link to ABSTRACT: Folic acid and multivitamin supplement use and risk of placental abruption: a population-based registry study.

Link to NEWS STORY: Folic acid may help prevent premature birth

 

 

 

 

CLINICAL UPDATE - LDL particles are better treatment target than ldl cholesterol

Reliance on LDL cholesterol instead of LDL particle numbers can undermine LDL-lowering therapies

(Journal of Clinical Lipidology, February 2008)

Link to ABSTRACT: Differential response of cholesterol and particle measures of atherogenic lipoproteins to LDL-lowering therapy: implications for clinical practice

 

 

 

 

CLINICAL UPDATE - Body mass index linked with cancer

Increased BMI is strongly associated with various cancer, especially renal and esophageal cancer

(Lancet, February 2008)

Link to ABSTRACT: Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

 

 

 

 

CLINICAL UPDATE - Common antioxidant helps prevent breast cancer

N-acetylcysteine inhibits estrogen-induced transformation of epithelial cells

(Journal of Steroid Biochemistry and Molecular Biology, March 2008)

Link to ABSTRACT: Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine

 

 

 

CLINICAL UPDATE - vitamin D and omega-3 protect children from diabetes

Meta-analysis indicates vitamin D supplements benefit children at high risk for diabetes

(Archives of Disease in Childhood, March 2008)

(Journal of the American Medical Association, September 2007)

Link to NEWS STORY

Link to ABSTRACT: Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis.

Link to ABSTRACT: Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type I diabetes

 

 

 

 

CLINICAL UPDATE - magnesium reduces risk of gallstones in men

Protection may relate to dyslipidemia and insulin hypersecretion caused by magnesium deficiency

(American Journal of Gastroenterology, February 2008)

Link to ABSTRACT: Long-term effect of magnesium consumption on the risk of symptomatic gallstone disease among men.