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Leptin, often called the “satiety hormone,” is an adipokine (signaling molecule produced by fat cells) whose main function is to regulate energy and fat stores. In a metabolically healthy person, a temporary increase in caloric intake (such as after a big meal) corresponds to an increase in leptin production. This prompts the hypothalamus to send signals that promote satiety, which cues one to stop eating. Leptin was the first adipokine to be discovered (in 1994) and changed how... Read More