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March 2008 - Volume 2, Issue 03
In this issue...
- Science stacks up for B vitamins and pregnancy
- LDL particles are better treatment target than LDL cholesterol
- Body mass index linked with cancer
- Common antioxidant helps prevent breast cancer
- Vitamin D and omega 3 protect children from diabetes
- Magnesium reduces risk of gallstones in men
CLINICAL UPDATE - Science stacks up for b vitamins and pregnancy
Low maternal vitamin B12 levels may increase risk of congenital heart problems; Folic acid may help prevent premature birth and placental abruption
(Molecular Genetics and Metabolism, January 2008)
(American Journal of Epidemiology, January 2008)
(Society of Maternal-Fetal Medicine Annual Meeting Proceedings, January 2008)
Link to ABSTRACT: Genetic and lifestyle factors related to periconception vitamin B12 status and congenital heart defects: A Dutch case-control study.
Link to ABSTRACT: Folic acid and multivitamin supplement use and risk of placental abruption: a population-based registry study.
Link to NEWS STORY: Folic acid may help prevent premature birth
CLINICAL UPDATE - LDL particles are better treatment target than ldl cholesterol
Reliance on LDL cholesterol instead of LDL particle numbers can undermine LDL-lowering therapies
(Journal of Clinical Lipidology, February 2008)
Link to ABSTRACT: Differential response of cholesterol and particle measures of atherogenic lipoproteins to LDL-lowering therapy: implications for clinical practice
CLINICAL UPDATE - Body mass index linked with cancer
Increased BMI is strongly associated with various cancer, especially renal and esophageal cancer
(Lancet, February 2008)
Link to ABSTRACT: Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
CLINICAL UPDATE - Common antioxidant helps prevent breast cancer
N-acetylcysteine inhibits estrogen-induced transformation of epithelial cells
(Journal of Steroid Biochemistry and Molecular Biology, March 2008)
Link to ABSTRACT: Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine
CLINICAL UPDATE - vitamin D and omega-3 protect children from diabetes
Meta-analysis indicates vitamin D supplements benefit children at high risk for diabetes
(Archives of Disease in Childhood, March 2008)
(Journal of the American Medical Association, September 2007)
Link to ABSTRACT: Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis.
Link to ABSTRACT: Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type I diabetes
CLINICAL UPDATE - magnesium reduces risk of gallstones in men
Protection may relate to dyslipidemia and insulin hypersecretion caused by magnesium deficiency
(American Journal of Gastroenterology, February 2008)
Link to ABSTRACT: Long-term effect of magnesium consumption on the risk of symptomatic gallstone disease among men.
