Lipoprotein(a) is a complex of ApoA and LDL, and an elevated status is associated with an increased risk for atherosclerosis and cardiovascular disease. The pathogenic role of lipoprotein(a) is similar to that of LDL in the development of atherosclerosis; it is localized in the blood vessel walls, then oxidized. Once oxidized, it forms the foam cells associated with atherosclerotic plaques.

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