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HOMOCYSTEINE

 

Click Here for Clinical Updates (2)

 

LPP_Components_Homocysteine_image  Click here to download brochure.

 

 

2011 Am J Clin Nutr

MTHFR 677C->T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation.

 

2011 J Coll Physicians Surg Pak

Serum total homocysteine and lipoprotein (a) levels in acute myocardial infarction and their response to treatment with vitamins.

 

2011 J Nutr

Methylenetetrahydrofolate Reductase Variants That Associate with Hypertension and Cardiovascular Disease Interact with Dietary Polyunsaturated Fatty Acids to Modulate Plasma Homocysteine in Puerto Rican Adults.

 

2011 Nutrition

High consumption of omega-3 polyunsaturated fatty acids decrease plasma homocysteine: A meta-analysis of randomized, placebo-controlled trials.

 

2010 Am J Cardiol

Meta-Analysis of Folic Acid Supplementation Trials on Risk of Cardiovascular Disease and Risk Interaction With Baseline Homocysteine Levels.

 

2010 Am J Epidemiol

Effects of Folic Acid Supplementation on Serum Folate and Plasma Homocysteine Concentrations in Older Adults: A Dose-Response Trial.

 

2010 Ann Nutr Metab

Effect of Antioxidant Vitamins on the Plasma Homocysteine Level in a Free-Living Elderly Population.

 

2010 Arch Int Med

Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals.

 

2010 Braz J Med Biol Res

Genetics of homocysteine metabolism and associated disorders.

FREE FULL TEXT

 

2010 Clin Biochem

Homocysteine and oxidative stress in Egyptian children with Down syndrome.

 

2010 Eur J Clin Nutr

Effect of physiological doses of oral vitamin B(12) on plasma homocysteine: a randomized, placebo-controlled, double-blind trial in India.

 

2010 Eur J Clin Nutr

Serum folate and homocysteine and depressive symptoms among Japanese men and women.

 

2010 JAMA

Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.

 

2010 J Epidemiol

Genetic polymorphisms in homocysteine metabolism and response to folate intake: a comprehensive strategy to elucidate useful genetic information.

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2010 J Nutr

Serum Homocysteine and Folate Concentrations Are Associated with Prevalent Age-Related Hearing Loss.

 

2010 J Sex Med

Treatment of erectile dysfunction due to C677T mutation of the MTHFR gene with vitamin B6 and folic acid in patients non responders to PDE5i.

 

2010 PLoS One

Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.

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2010 Pyschosom Med

Serum Folate, Vitamin B-12, and Homocysteine and Their Association With Depressive Symptoms Among U.S. Adults.

 

2009 Aliment Pharmacol Ther

Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet.

 

2009 Diabetes Metab Res Rev

Serum homocysteine, folate, vitamin B12 levels and arterial stiffness in diabetic patients: which of them is really important in atherogenesis?

 

2009 Pharmacogenet Genomics

The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability.

 

2009 Rejuvenation Res

Telomere length in lymphocytes of older South Australian men may be inversely associated with plasma homocysteine.

 

2008 Am J Clin Nutr

Homocysteine, cysteine, and body composition in the Hordaland Homocysteine Study: does cysteine link amino acid and lipid metabolism?

 

2008 Arch Intern Med

Vitamin B12 and folate and the risk of anemia in old age: the Leiden 85-Plus Study.

 

2008 Arch Otolaryngol Head Neck Surg

Plasma Homocysteine, folate, and vitamin B12 levels in patients with laryngeal cancer.

 

2008 Atherosclerosis

Homocysteine levels and leukocyte telomere length.

 

2008 Clin Nutr

Raised homocysteine and low folate and vitamin B-12 concentrations predict cognitive decline in community dwelling older Japanese adults

 

2008 JAMA

High-dose B vitamin supplementation and cognitive decline in Alzheimer Disease: a randomized controlled trial.

 

2008 JAMA

Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial

 

2008 J Neurol Neurosurg Psychiatry

Changes in folate, vitamin B12 and homocysteine associated with incident dementia.

 

2008 J Nutr

Weekly may be as efficacious as daily folic acid supplementation in improving folate status and lowering serum homocysteine concentrations in guatemalan women

 

2008 Mol Genet Metab

Genetic and lifestyle factors related to the periconception vitamin B12 status and congenital heart defects: A Dutch case-control study

 

2008 Neuroimmunomodulation

Effect of folic acid combined with fluoxetine in patients with major depression on plasma homocysteine and vitamin B12, and serotonin levels in lymphocytes.

 

2007 Am J Clin Nutr

The association between betaine and choline intakes and the plasma concentrations of homocysteine in women

 

2007 Am J Clin Nutr

Low vitamin B12 status and risk of cognitive decline in older adults.

 

2007 Clin Chem Lab Med

Association of thyroid dysfunction with vitamin B12, folate and plasma homocysteine levels in the elderly: a population-based study in Sicily

 

2007 Endocr J

Homocysteine, folate and cobalamin levels in hypothyroid women before and after treatment

 

2007 Headache

Efficacy of folic acid in children with migraine, hyperhomocysteinemia and MTHFR polymorphisms.

 

2007 Hum Reprod Update

Impact of folate and homocysteine metabolism on human reproductive health

 

2006 BMC Cardiovasc Disord

Homocysteine, vitamin B12 and folate levels in premature coronary artery disease.

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2006 Clin Chem Lab Med

The effects of adrenocorticotrophic hormone and cortisol on homocysteine and vitamin B concentrations

 

2006 N Engl J Med

Homocysteine lowering with folic acid and B vitamins in vascular disease.

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2005 Am J Clin Nutr

Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load.

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2005 Am J Clin Nutr

Homocysteine and folate as risk factors for dementia and Alzheimer disease.

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2005 Circulation

Cardiology patient pages. Homocysteine and MTHFR mutations: relation to thrombosis and coronary artery disease.

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2005 Clin Gastroenterol Hepatol

Prevalence of hyperhomocysteinemia in adult gluten-sensitive enteropathy at diagnosis: role of B12, folate, and genetics.

 

2005 Int J Neuropsychopharmacol

The relationship between serum folate, vitamin B12, and homocysteine levels in major depressive disorder and the timing of improvement with fluoxetine

 

2005 J Psychopharmacol

Treatment of depression: time to consider folic acid and vitamin B12

 

2005 Prog Neuropshychopharmacol Biol Psychiatry

Homocysteine and folate metabolism in depression

 

2005 Psychol Med

Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample

 

2004 Am J Geriatr Psychiatry

Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disorders

 

2004 J Clin Psychiatry

Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression

 

2004 J Clin Psychiatry

Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 2: predictors of relapse during the continuation phase of pharmacotherapy

 

2004 Richard Corley, MD

The Compelling Case for Homocysteine Assay.

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2003 Arch Gen Psychiatry

Folate, vitamin B12, homocysteine, and the MTHFR 677C->T polymorphism in anxiety and depression: the Hordaland Homocysteine Study

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2003 J Intern Med

Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial.

 

2002 Am J Psychiatry

Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study

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2002 JAMA

Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomized controlled trial.

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2001 Dialysis & Transplantation

Normalization of homocysteine in dialysis patients by directed repletion, with apparent reduction of access thrombosis.

 

1999 Lancet

Homocysteine and vascular disease.

 

1997 JAMA

Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project.

 

1997 Scand J Clin Lab Invest

Poor metabolic control, early age at onset, and marginal folate deficiency are associated with increasing levels of plasma homocysteine in insulin-dependent diabetes mellitus.  A five-year follow-up study.

 

1996 Am J Hum Genet

Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.

FREE FULL TEXT

 

1995 JAMA

A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes.

 

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